Isolation Valves, Pinch Valves, Piston Pumps, Product News, Rocker Valves, Rotary Valves

Improving Reliability of IVD Instruments

Reliability of an instrument is one of the essential needs of IVD Instrument OEMs. To design the best IVD instrument, you need to specify components that are designed to last and help provide reliable test results. With the use of aggressive fluids and harsh operating environments, it can be difficult finding the appropriate components that can handle these conditions while operating reliably.

Bio-Chem Fluidics has designed components with reliability in mind and also possesses the capability to provide custom solutions and support to ensure components can operate consistently in special applications and the harshest conditions.


wide-e1516805944476.jpgBio-Chem Fluidics designed the Maestro Piston Pump for longevity while maintaining its performance. With precision rated at less than 0.2% Cv and accuracy at +/- 0.5%, Bio-Chem’s Maestro pump is perfect for your high-precision dispensing applications. The standard Maestro piston pump has been tested to last up to 18 million cycles on water, which is far beyond the life of a typical IVD instrument.

For many IVD instrument OEMs, pumps should also have the ability to handle aggressive fluids with high salt concentrations.  Through their materials and machining expertise, Bio-Chem Fluidics has engineered a patent-pending solution that can handle high salt concentrations that are detrimental to precision dispense pumps.

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Maestro ULTRA addresses the issue of high salt concentration solutions by using a hydrophobic, low surface energy piston which decreases wettability and prevents materials from adhering to its surface. This technology has been tested to last up to 3 million cycles, which is within the life of most IVD instruments that utilize salt solutions. Maestro ULTRA removes the risk of sample contamination, costly repairs, and system complexity that arise from using flushed seal pumps. More information and test data on our Maestro ULTRA piston pump can be found in our white paper, Removing the Risk of Concentrated Salt Solutions to Precision Dispense Pumps.


RenderingAggressive chemicals can have negative effects to the performance of components, especially when an instrument has a need for a valve to handle multiple fluids or reagents. Finding a component with wetted materials that can handle multiple reagents can be very challenging. The Bio-Chem Fluidics Electronic Rotary Valve was designed to provide an inert, multiport valve solution. With the only wetted materials in the ERV being the PTFE valve body and the PCTFE rotor, the Bio-Chem Fluidics ERV is the most inert option on the market, ensuring a non-metallic, corrosion resistant fluid path. In addition to the advantage of an inert flow path, the Bio-Chem ERV has a very low dead volume which can prevent sample/reagent waste. This ERV also has an unobstructed flow path, providing a lower pressure drop than most valves.

Opus_RVsThe rocker valve is a common sight in IVD instruments, and with the need for instruments to reduce in size while maintaining their performance and reliability, components will need to do the same. The Opus Rocker Valve successfully meets those needs. The Opus valve has a small footprint of 10mm and low internal volume of 35 µl, but still achieves a high fluid flow rate of 0.04 Cv despite its size. With a mean time to failure of 15 million cycles, it is the perfect match to Bio-Chem’s Maestro and Maestro ULTRA pumps.

Pinch Valve familyWhen seeking a valve solution that limits the interaction of a reagent or sample with valve components, a Pinch Valve is ideal. Pinch valves allows instruments to have a sterile flow path simply by changing tubing between samples. Pinch valves have zero dead volume which limits interaction with any previous fluids or samples. They also possess an unobstructed flow thus reducing shear of fragile biological materials. The Bio-Chem pinch valve is assembled so that each valve has a custom setting for every tubing size and material. Whether it’s a standard tubing material such as silicone or C-Flex or a custom tubing material, each tubing has its own unique valve setting ensuring that the tubing can reach maximum life with minimal tubing changes throughout the life of the instrument.

isolation valve familyAs mentioned previously, applications that require valves for harsh chemicals will require inert wetted materials and selecting a high performance valve that can handle aggressive fluids can be challenging.  The Bio-Chem Fluidics Isolation Valve can include wetted materials such as PTFE, PEEK, and PPS bodies and PTFE, EPDM, FKM, and FFKM diaphragms with multiple orifice sizes from .032” to .125” to suit any application without the concern for chemical compatibility.

Bio-Chem Fluidics’ capabilities go beyond their large portfolio of products. With engineers that are experts in fluidics and a world-class machine shop, Bio-Chem Fluidics has earned a reputation for superior customer service and support and high quality products. To find out more about their products and services visit or contact them by emailing

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